CJC 1295 + Ipamorelin
A combination of a GHRH analog (CJC-1295) and a selective growth hormone secretagogue (Ipamorelin). Research investigates synergistic effects on pulsatile GH release, IGF-1 levels, and downstream metabolic and recovery markers without significant cortisol or prolactin elevation.
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Mechanism of Action
This blend pairs two distinct GH-releasing mechanisms. CJC-1295 is a GHRH analog that binds GHRH receptors on pituitary somatotrophs (4-fold greater receptor affinity than native GHRH). Ipamorelin is a selective ghrelin receptor (GHS-R1a) agonist acting through a separate pathway. Co-administration produces synergistic pulsatile GH release while Ipamorelin's selectivity avoids cortisol, prolactin, and aldosterone elevation typical of earlier secretagogues.
Research References
Full research page →Teichman SL et al. Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. J Clin Endocrinol Metab. 2006. PMID: 16352683
Raun K et al. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998. PMID: 9849822
Ionescu M, Frohman LA. Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog. J Clin Endocrinol Metab. 2006
Gobburu JV et al. Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers. Pharm Res. 1999
Batch History & Certificates of Analysis
Full Batch Record
Active Batches
CP10-2026-001
Received Apr 15, 2026
Qty Received
10 units
No test results on record for this batch.
For Research Use Only. This product is supplied exclusively for in vitro research, laboratory study, and experimental purposes. It is not a drug, supplement, food, or cosmetic, and is not intended for human or veterinary use. See our Compliance & RUO Policy.