IGF-1 LR3
A modified insulin-like growth factor-1 variant with extended half-life. Research examines its role in anabolic signaling, muscle protein synthesis, cellular proliferation, and tissue repair pathways.
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All batch test results and certificates of analysis are published below — including any batches that failed testing. Full transparency is our standard.
Mechanism of Action
IGF-1 LR3 is an 83-amino-acid IGF-1 variant with an arginine substitution at position 3 (replacing glutamic acid) and a 13-amino-acid N-terminal extension. These modifications dramatically reduce binding to IGF-binding proteins (IGFBPs), extending half-life from ~12-15 minutes (native IGF-1) to approximately 20-30 hours, and making it roughly 3x more potent. It retains full agonism at the IGF-1 receptor, activating PI3K/Akt/mTOR and MAPK pathways driving protein synthesis and cell proliferation.
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Batch History & Certificates of Analysis
Full Batch Record
Active Batches
IGF1-2026-001
Received Apr 15, 2026
Qty Received
10 units
No test results on record for this batch.
For Research Use Only. This product is supplied exclusively for in vitro research, laboratory study, and experimental purposes. It is not a drug, supplement, food, or cosmetic, and is not intended for human or veterinary use. See our Compliance & RUO Policy.