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Peptide Research

GLP2-TZ

SKU: TR10

Tirzepatide is a 39-amino-acid dual GIP/GLP-1 receptor agonist engineered from the GIP sequence with GLP-1 activity. GLP-1 activation enhances glucose-dependent insulin release, slows gastric emptying, and promotes satiety. GIP co-agonism amplifies insulin secretion and modulates

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GLP2-TZ

Mechanism of Action

Tirzepatide is a 39-amino-acid dual GIP/GLP-1 receptor agonist engineered from the GIP sequence with GLP-1 activity. GLP-1 activation enhances glucose-dependent insulin release, slows gastric emptying, and promotes satiety. GIP co-agonism amplifies insulin secretion and modulates adipose tissue function. SURPASS trials demonstrated HbA1c reductions of 1.24-2.58% and weight reductions of 5.4-11.7 kg at weekly doses of 5-15 mg.

Research Studies

2 peer-reviewed studies curated for GLP2-TZ.

Related Research

Compared in research against GLP3-RT (triple agonist) and Tesamorelin (different metabolic axis via GHRH). Often studied alongside MOTS-c for metabolic pathway convergence and CJC-1295 + Ipamorelin where body composition research is the focus.